Neuroscience Journals

Multimodal artificial intelligence integrating peritumoral MRI and clinical data stratifies meningioma recurrence risk after radiotherapy

Mon, 07 Sep 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Hiroaki Wakimoto (h-index 74) That author's affiliation: Harvard University Institution (first & last author): Fudan University Multimodal artificial intelligence integrating peritumoral MRI and clinical data stratifies meningioma recurrence risk after radiotherapy

From feasibility to neuroanatomic validity of remote cognitive smartphone assessments in early Alzheimer’s disease

Sat, 05 Sep 2026 00:00:00 +0000

reply.relevance=9 reply.impact=9 Highest h-index author on this paper: Kirsten I. Taylor (h-index 41) That author's affiliation: Roche (Switzerland) Institution (first & last author): Roche (Switzerland) From feasibility to neuroanatomic validity of remote cognitive smartphone assessments in early Alzheimer’s disease

Exploring generalizability and explainability of LLMs in classifying clinically rated suicidal ideation using heterogeneous data

Sat, 05 Sep 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Yun Kwok Wing (h-index 80) That author's affiliation: Chinese University of Hong Kong Institution (first & last author): Chinese University of Hong Kong Exploring generalizability and explainability of LLMs in classifying clinically rated suicidal ideation using heterogeneous data

Differences in tone of AI and care team responses to patient messages by patient demographics

Thu, 03 Sep 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Yindalon Aphinyanaphongs (h-index 27) That author's affiliation: NYU Langone Health First author institution: NYU Langone Health Last author institution: Institute for Family Health Differences in tone of AI and care team responses to patient messages by patient demographics

A five-phase evaluation framework for diagnostic and predictive medical artificial intelligence

Thu, 03 Sep 2026 00:00:00 +0000

reply.relevance=8 reply.impact=9 Highest h-index author on this paper: Manman Chen (h-index 24) That author's affiliation: Chinese Academy of Medical Sciences & Peking Union Medical College Institution (first & last author): Chinese Academy of Medical Sciences & Peking Union Medical College A five-phase evaluation framework for diagnostic and predictive medical artificial intelligence

A perspective on federated foundation models in biomedical sensing and imaging

Tue, 01 Sep 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 A perspective on federated foundation models in biomedical sensing and imaging

Generative deep learning reconstructs subcortical neural signals from cortical recordings for closed-loop brain stimulation

Tue, 01 Sep 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Generative deep learning reconstructs subcortical neural signals from cortical recordings for closed-loop brain stimulation

AgentDS-BUS: a fine-tuning-free agentic breast ultrasound malignancy classification framework with decoupled segmentation and feature analysis

Sat, 29 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Lekui Xiao (h-index 4) That author's affiliation: Mayo Clinic in Arizona Institution (first & last author): Jacksonville College AgentDS-BUS: a fine-tuning-free agentic breast ultrasound malignancy classification framework with decoupled segmentation and feature analysis

Interpretable multi-modal hierarchical framework to support cytomorphological analysis of hematologic cancers

Sat, 29 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Oscar Brück (h-index 26) That author's affiliation: University of Helsinki Institution (first & last author): University of Helsinki Interpretable multi-modal hierarchical framework to support cytomorphological analysis of hematologic cancers

Enhancing clinical reasoning and diagnostic precision through scaling laws and multi-stage supervised fine-tuning in open-weight medical large language models

Fri, 28 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Enhancing clinical reasoning and diagnostic precision through scaling laws and multi-stage supervised fine-tuning in open-weight medical large language models

Transdiagnostic connectome-based predictive modeling reveals networks jointly linked to subjective clinical symptoms and cognition

Thu, 27 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Highest h-index author on this paper: R. Todd Constable (h-index 119) Institution (first & last author): Unknown Simon et al. leverage connectome-based predictive modeling to identify brain circuits related to cognitive deficits that co-occur with self-reported psychiatric symptoms. They find that the sparsely shared networks strongly predict cognition and are often localized within the frontoparietal and between the frontoparietal and default mode networks.

The beginning of the end for manual chart review: LLM-mediated database construction

Thu, 27 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Robert Abouassaly (h-index 37) That author's affiliation: Cleveland Clinic Institution (first & last author): Cleveland Clinic The beginning of the end for manual chart review: LLM-mediated database construction

Ensuring trustworthy AI assisted guideline development for clinical practice

Thu, 27 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Ensuring trustworthy AI assisted guideline development for clinical practice

Delays between CE mark and FDA regulatory approval of AI-enabled software for radiology

Sat, 22 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Delays between CE mark and FDA regulatory approval of AI-enabled software for radiology

Modernizing evidence generation for clinical artificial intelligence: the case for adaptive platform trials

Thu, 20 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Modernizing evidence generation for clinical artificial intelligence: the case for adaptive platform trials

Exploring a dynamic digital biomarker of illness severity in older ICU patients via interpretable time-series deep learning modeling

Thu, 20 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Exploring a dynamic digital biomarker of illness severity in older ICU patients via interpretable time-series deep learning modeling

Fine-tuning an ECG foundation model to predict coronary CT angiography outcomes

Tue, 18 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Tong Liu (h-index 74) Institution (first & last author): Unknown Fine-tuning an ECG foundation model to predict coronary CT angiography outcomes

MultiMed-RAG: leveraging multi-source knowledge and agent collaboration for medical tasks

Mon, 17 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Jinzhuo Wang (h-index 15) That author's affiliation: Peking University First author institution: Georgia Institute of Technology Last author institution: Peking University MultiMed-RAG: leveraging multi-source knowledge and agent collaboration for medical tasks

Accelerating AI in clinical care: policy priorities of the 2025 HHS request for information

Sat, 15 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: David C. Klonoff (h-index 23) That author's affiliation: Sutter Health First author institution: Sutter Health Last author institution: Lurie Children's Hospital A U.S. Department of Health and Human Services Request for Information seeks input on “Accelerating the Adoption and Use of Artificial Intelligence as Part of Clinical Care.” This solicitation could impact future policies on regulation, reimbursement, and research, with emphasis on AI governance and implementation science. Using diabetes as an exemplar, this article examines emerging frameworks for AI‑enabled tools for continuous glucose monitoring, automated insulin delivery, and clinical decision support.

Context-aware monitoring: rethinking comprehensive screening in the era of AI

Thu, 13 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Applying advanced measurement technologies proactively in asymptomatic populations predictably yields false positives, as a consequence of Bayes’ Theorem. Yet the same Bayesian arithmetic suggests a remedy: adding context. Serial and multimodal measurements, integrated using context-aware AI that prioritizes within-person change over population norms, can reduce false positive rates while preserving sensitivity. We describe early illustrations from imaging and molecular diagnostics and discuss challenges including cost, anxiety, liability, and equity.

Natural language processing application in electronic health records studies for psychosis: a systematic review

Wed, 12 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Natural language processing application in electronic health records studies for psychosis: a systematic review

AlzheiNN: a convolutional neural network-based model for Alzheimer’s disease classification

Wed, 12 Aug 2026 00:00:00 +0000

reply.relevance=9 reply.impact=9 AlzheiNN: a convolutional neural network-based model for Alzheimer’s disease classification

Multimodal artificial intelligence agents in healthcare: a scoping review

Sat, 08 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Multimodal artificial intelligence agents in healthcare: a scoping review

Patient engagement, acceptability, and preference of artificial intelligence versus human coaching for diabetes prevention

Mon, 03 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Patient engagement, acceptability, and preference of artificial intelligence versus human coaching for diabetes prevention

Predicting Alzheimer progression using EEG-based digital twins

Mon, 03 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Alberto Mazzoni (h-index 33) Institution (first & last author): Unknown Predicting Alzheimer progression using EEG-based digital twins

Reply to: Clinician engagement modifies effectiveness of AI enabled ECG screening

Sat, 01 Aug 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Highest h-index author on this paper: Yiğit Yazarkan (h-index 3) That author's affiliation: Mayo Clinic in Arizona Institution (first & last author): Mayo Clinic in Arizona Reply to: Clinician engagement modifies effectiveness of AI enabled ECG screening

An objective smartphone speech diagnostic aid for adolescent major depressive disorder

Wed, 29 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 An objective smartphone speech diagnostic aid for adolescent major depressive disorder

A Multi-Agent MLLM Framework for Imaging-Grounded Treatment Recommendation in Acute Ischemic Stroke

Wed, 29 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 A Multi-Agent MLLM Framework for Imaging-Grounded Treatment Recommendation in Acute Ischemic Stroke

Understanding mechanistic role of structural and functional connectivity in tau propagation through multilayer modeling

Wed, 29 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Understanding mechanistic role of structural and functional connectivity in tau propagation through multilayer modeling

Population-specific dementia risk prediction using deep transfer learning in diverse populations

Tue, 28 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Population-specific dementia risk prediction using deep transfer learning in diverse populations

Meaningful oversight of medical AI beyond human in the loop

Thu, 23 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=9 Human oversight of medical AI is increasingly required, but clinician presence alone does not make oversight meaningful. We propose four interlocking conditions—epistemic capacity, cognitive space, decisional authority, and intervention effectiveness—that determine whether human judgment can function as a safety mechanism. Embedding these conditions across procurement, deployment, monitoring, and decommissioning can turn oversight into an operational patient-safety capability across predictive, generative, semi-autonomous, and agentic systems.

Sex-specific developmental pathways link brain networks, sensory sensitivity, and sleep to adolescent pain

Wed, 22 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Developmental pathways highlight the sex-related links between brain networks and the emergence of adolescent multisite pain via increased sensory sensitivity and worsening sleep.

The expression modifier score (EMS) v2 enhances regulatory variant prioritization via Enformer-derived features and multi-task learning

Wed, 22 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Expression Modifier Score v2 integrates Enformer-derived features and multi-task learning to prioritize regulatory variants and support interpretation of noncoding genetic associations.

Real-world deployment of remote sleep monitoring technologies reveals distinct patterns associated with cognitive decline

Tue, 21 Jul 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: Payam Barnaghi (h-index 42) That author's affiliation: Imperial College London Institution (first & last author): Imperial College London Real-world deployment of remote sleep monitoring technologies reveals distinct patterns associated with cognitive decline

A scoping review of explainable artificial intelligence for medical multimodal data

Wed, 15 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 A scoping review of explainable artificial intelligence for medical multimodal data

Interpretable agentic AI system with localized reasoning for radiology

Wed, 15 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Interpretable agentic AI system with localized reasoning for radiology

Fairness in multimodal machine learning applications in clinical decision support: a systematic review

Tue, 14 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Fairness in multimodal machine learning applications in clinical decision support: a systematic review

Multimodal AI for predicting comorbid REM sleep behavior disorder in major depressive disorder

Tue, 14 Jul 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Multimodal AI for predicting comorbid REM sleep behavior disorder in major depressive disorder

A unified multi-modal foundation model for end-to-end emergency care

Tue, 14 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 A unified multi-modal foundation model for end-to-end emergency care

Portable RF brain scanner enables stroke type detection using deep learning

Mon, 13 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Portable RF brain scanner enables stroke type detection using deep learning

Passive early screening for Alzheimer’s disease and related dementias using EHR comorbidity patterns

Sat, 11 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Passive early screening for Alzheimer’s disease and related dementias using EHR comorbidity patterns

Embedded transparency in artificial intelligence: a prerequisite for equity and representation in AI-enabled clinical trials

Sat, 11 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=9 Artificial intelligence is being embedded in clinical trial infrastructure, shaping who is identified, stratified, and analysed. Opaque models risk amplifying existing disparities in the evidence base. We argue that embedded transparency, the structural integration of ex ante interpretability, demographic auditability, documented uncertainty handling, and stakeholder-relative explanation, is a necessary, though not sufficient, condition for equitable AI-enabled trials, and propose governance recommendations actionable across regulatory regimes.

Physiological arousal as a predominant source of individual differences in functional brain networks

Fri, 10 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Individual differences in arousal, indexed by a non-neuronal fMRI signal, are strongly associated with variation in functional brain network connectivity. Effects replicate within and across samples and are altered by catecholaminergic manipulation.

Simulation of covariate and concept drift in machine learning hospital admission prediction from emergency triage

Fri, 10 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Simulation of covariate and concept drift in machine learning hospital admission prediction from emergency triage

BrainSeg: a generalized framework for comprehensive multimodal brain tissue segmentation, parcellation, and lesion labeling

Fri, 10 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 BrainSeg: a generalized framework for comprehensive multimodal brain tissue segmentation, parcellation, and lesion labeling

Developmental trajectory of the prefrontal operculum and the consequences of premature birth

Thu, 09 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=6 Highest h-index author on this paper: Jessica Dubois (h-index 33) That author's affiliation: Inserm Institution (first & last author): Université Claude Bernard Lyon 1 Anatomical assessment of the fetal and preterm cerebral cortical surface reveals the precise timeline of cortical sulcation, and identifies the prefrontal operculum as the last region to emerge during development and the most impacted by prematurity.

Sleep EEG foundation models reveal within-stage microstructure that improves health screening beyond traditional stages

Thu, 09 Jul 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: mattson ogg (h-index 0) Institution (first & last author): Unknown Sleep EEG foundation models reveal within-stage microstructure that improves health screening beyond traditional stages

AI-driven diagnostic algorithm enhances early detection of paroxysmal nocturnal hemoglobinuria in real-world settings

Thu, 09 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Highest h-index author on this paper: Mirosław Markiewicz (h-index 24) That author's affiliation: University of Rzeszów Institution (first & last author): Medical University of Warsaw AI-driven diagnostic algorithm enhances early detection of paroxysmal nocturnal hemoglobinuria in real-world settings

Multilevel brain heart interaction correlates with suicidal ideation in first episode drug naive major depressive disorder

Wed, 08 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=6 Integrative EEG-ECG-derived brain-heart interaction profiling illuminates region-specific neurophysiological and molecular signatures underlying suicidal ideation in first-episode drug-naïve major depressive disorder.

PANDA pediatric arousal neural detection architecture

Tue, 07 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Highest h-index author on this paper: Katie L. Stone (h-index 99) That author's affiliation: University of California, San Francisco Institution (first & last author): Beth Israel Deaconess Medical Center PANDA pediatric arousal neural detection architecture

Large language models are powerful electronic health record encoders

Mon, 06 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=8 Highest h-index author on this paper: Roland Eils (h-index 126) Institution (first & last author): Unknown Large language models are powerful electronic health record encoders

Bridging the gap from clinical to home ECG: quantifying and overcoming accuracy loss in AI-enabled single-lead ECG models

Mon, 06 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=8 Bridging the gap from clinical to home ECG: quantifying and overcoming accuracy loss in AI-enabled single-lead ECG models

Explainable foundation model for dementia screening and risk stratification using retinal fundus images

Sat, 04 Jul 2026 00:00:00 +0000

reply.relevance=8 reply.impact=9 Explainable foundation model for dementia screening and risk stratification using retinal fundus images

LLM research on public biosignals data is needed to protect patients

Sat, 04 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=8 LLM research on public biosignals data is needed to protect patients

BCGNet: an AI model trained on 600 K hours of sleep data for a novel under-pillow contactless monitoring device

Fri, 03 Jul 2026 00:00:00 +0000

reply.relevance=7 reply.impact=8 Highest h-index author on this paper: Yue Leng (h-index 35) Institution (first & last author): Unknown BCGNet: an AI model trained on 600 K hours of sleep data for a novel under-pillow contactless monitoring device

Automated diagnosis of keratitis from low-quality slit-lamp images using an improved generative adversarial network

Fri, 03 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Jiewei Jiang (h-index 17) That author's affiliation: Xi’an University of Posts and Telecommunications First author institution: Xi’an University of Posts and Telecommunications Last author institution: Wenzhou Medical University Automated diagnosis of keratitis from low-quality slit-lamp images using an improved generative adversarial network

Physicians and artificial intelligence diverge in evaluating large language models on real clinical cases

Thu, 02 Jul 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Physicians and artificial intelligence diverge in evaluating large language models on real clinical cases

FedFound: a federated foundation model for lifespan brain morphological connectome analysis

Tue, 30 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Sheng‐Che Hung (h-index 26) Institution (first & last author): Unknown FedFound: a federated foundation model for lifespan brain morphological connectome analysis

UNICORN: a deep learning model for integrating multi-stain data in histopathology

Thu, 18 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Highest h-index author on this paper: Heribert Schunkert (h-index 133) Institution (first & last author): Unknown UNICORN: a deep learning model for integrating multi-stain data in histopathology

Unlocking multi-institutional insights into disease progression with PEAL as a lossless, one-shot federated learning solution

Thu, 18 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Unlocking multi-institutional insights into disease progression with PEAL as a lossless, one-shot federated learning solution

Perinatal mood and anxiety diagnoses and treatment increased among medicaid births, 2017–2021

Thu, 18 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Highest h-index author on this paper: Kara Zivin (h-index 54) Institution (first & last author): Unknown Perinatal mood and anxiety diagnoses and treatment increased among medicaid births, 2017–2021

SORBS2 regulates diastolic function through cytoskeletal networks and calcium handling

Wed, 17 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Highest h-index author on this paper: William T. Pu (h-index 91) Institution (first & last author): Unknown Functional characterization of SORBS2, a component of the adhesome complex, sheds light on the regulation of cytoskeletal networks and calcium handling in the context of cardiac diastolic function.

A dermo-hypothalamic axis driven by TNF-α mediates sleep disturbances in psoriasis

Wed, 17 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 Highest h-index author on this paper: Zhiqiang Yin (h-index 25) That author's affiliation: Nanjing Medical University First author institution: Nanjing General Hospital of Nanjing Military Command Last author institution: Nanjing Medical University Clinical data and a mouse model of psoriasis reveal a direct pathway from skin inflammation to sleep-regulating brain circuits, identifying tumor necrosis factor-alpha as a potential therapeutic target for psoriasis-associated insomnia.

Two decades of growth and trends in the FDA authorization of digital medical devices

Wed, 17 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Cirrus Foroughi (h-index 5) Institution (first & last author): Unknown Two decades of growth and trends in the FDA authorization of digital medical devices

Real-world evaluation of large language model for patients medical and administrative queries in nuclear medicine

Wed, 17 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=8 Real-world evaluation of large language model for patients medical and administrative queries in nuclear medicine

Large language models for acute coronary syndrome triage at first medical contact in emergency departments

Wed, 17 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=8 Large language models for acute coronary syndrome triage at first medical contact in emergency departments

Mapping the functional connectome between grey matter and white matter

Tue, 16 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Mapping the functional connectome between grey and white matter reveals a hierarchical architecture shaped by neurotransmitter systems, predicts cognitive performance, and improves diagnostic classification of brain disorders.

Digital phenotyping with large language models to detect depressive state changes in patients

Mon, 15 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Digital phenotyping with large language models to detect depressive state changes in patients

Deep learning analysis of breast cancer histology predicts ATM pathogenic variant carrier status

Mon, 15 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Deep learning analysis of breast cancer histology predicts ATM pathogenic variant carrier status

FairGen: preference-aligned diffusion for demographically equitable medical image synthesis

Sat, 13 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Highest h-index author on this paper: T Donna Chen (h-index 1) Institution (first & last author): Unknown FairGen: preference-aligned diffusion for demographically equitable medical image synthesis

Reassessing the evidence linking clinical leadership to AI deployment outcomes

Sat, 13 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Highest h-index author on this paper: (h-index n/a) That author's affiliation: Wills Eye Hospital Institution (first & last author): Wills Eye Hospital Reassessing the evidence linking clinical leadership to AI deployment outcomes

ActiTect: a generalizable machine learning pipeline for REM sleep behavior disorder screening through standardized actigraphy

Sat, 13 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Highest h-index author on this paper: Gereon R. Fink (h-index 133) That author's affiliation: University of Cologne First author institution: TH Köln - University of Applied Sciences Last author institution: University of Cologne ActiTect: a generalizable machine learning pipeline for REM sleep behavior disorder screening through standardized actigraphy

Porphyromonas gingivalis promotes the malignant phenotype of oral squamous cell carcinoma through the recruitment of Treg cells

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=6 Histological and P. gingivalis-infected OSCC models elucidate that it fosters an immunosuppressive microenvironment by promoting CCL20 secretion to recruit CCR6⁺ regulatory T cells.

Non-duality in brain and experience of advanced meditators—key role for intrinsic neural timescales

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Advanced meditators show similar duration of intrinsic neural timescales during internal and external attention, suggesting a neural signature of non-dual awareness.

Virtual nursing implementation and 30-day patient readmissions: a multi-site study

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=4 Virtual nursing implementation and 30-day patient readmissions: a multi-site study

An autonomous AI agent for knowledge and data cooperation in ED clinical decision support

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 An autonomous AI agent for knowledge and data cooperation in ED clinical decision support

A new AI assisted approach aligns data standards and accelerates interoperability in biomedical research

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 A new AI assisted approach aligns data standards and accelerates interoperability in biomedical research

ERO1a fosters glioblastoma aggressiveness and metabolic flexibility by regulating mitochondria-associated membrane dynamics

Fri, 12 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Bassot, Violy, Gorka, Cigalotto and colleagues identify ERO1a as a mitochondria-associated membrane protein that regulates calcium flux and mitochondria bioenergetics, which may be potentially targeted to inhibit glioblastoma growth in vivo.

Author Correction: Transformer patient embedding using electronic health records enables patient stratification and progression analysis

Thu, 11 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Highest h-index author on this paper: Theresa L. Walunas (h-index 38) That author's affiliation: Northwestern University First author institution: University of Washington Medical Center Last author institution: Tulane University Author Correction: Transformer patient embedding using electronic health records enables patient stratification and progression analysis

FIRST-ICU: forecasting interventions and risk stratification in the ICU using graph neural network autoencoders

Thu, 11 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Highest h-index author on this paper: Nosa Aikodon (h-index 2) That author's affiliation: Liverpool John Moores University Institution (first & last author): Liverpool John Moores University FIRST-ICU: forecasting interventions and risk stratification in the ICU using graph neural network autoencoders

Development and prospective evaluation of a real-time deep learning model for inpatient hypoglycemia prediction

Thu, 11 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Highest h-index author on this paper: Elizabeth V. Nguyen (h-index 18) Institution (first & last author): Unknown Development and prospective evaluation of a real-time deep learning model for inpatient hypoglycemia prediction

Embeddings of clinical codes enable knowledge-grounded AI in medicine

Thu, 11 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Highest h-index author on this paper: Ran D. Balicer (h-index 56) That author's affiliation: Ben-Gurion University of the Negev First author institution: Harvard University Last author institution: Broad Institute Embeddings of clinical codes enable knowledge-grounded AI in medicine

Oxaliplatin triggers adipose and muscle wasting through cancer-independent metabolic and CNS pathways in mouse models

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 Chronic oxaliplatin treatment in mice drives a cancer-independent cachexia-like syndrome marked by severe adipose and muscle wasting, metabolic dysfunction, inflammation, and CNS dysregulation, presenting distinct pathways and unique therapeutic targets.

Mitochondrial bioenergetic signatures differentiate asymptomatic from symptomatic Alzheimer’s disease

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Enhanced mitochondrial bioenergetics across oxidative phosphorylation, fatty acid, and branched chain amino acid metabolism in brain cell types drives cognitive resilience in asymptomatic Alzheimer’s disease.

Functional and morphological alterations of light detection circuits in postmortem retina from donors with different stages of Alzheimer’s-like pathology

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Ex vivo recordings and histology of postmortem human retina reveal selective dysfunction of ipRGC light-detection circuits in Alzheimer’s disease, highlighting retinal light responses as potential biomarkers of neurodegeneration.

Federated generative prompt learning with vision foundation models: universal efficient multi-center medical image analysis

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Federated generative prompt learning with vision foundation models: universal efficient multi-center medical image analysis

Deployable real-time spinal endoscopic instance segmentation with lightweight multi-scale attention mechanism

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Deployable real-time spinal endoscopic instance segmentation with lightweight multi-scale attention mechanism

Smartphone-based detection of subtle memory decline in prodromal Alzheimer’s disease

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Smartphone-based detection of subtle memory decline in prodromal Alzheimer’s disease

Human–AI collaboration for dysphagia rehabilitation from effectiveness to implementation complexity: a systematic review

Wed, 10 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Human–AI collaboration for dysphagia rehabilitation from effectiveness to implementation complexity: a systematic review

Unveiling the novel role of PGAM5 in rewiring metabolism through PI3K/AKT/mTOR signaling in acute myelogenous leukemia

Tue, 09 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Highest h-index author on this paper: Guangfeng He (h-index 0) That author's affiliation: Affiliated Hospital of Southwest Medical University First author institution: Affiliated Hospital of Southwest Medical University Last author institution: Chuzhou University Unveiling the novel role of PGAM5 in rewiring metabolism through PI3K/AKT/mTOR signaling in acute myelogenous leukemia

Transcriptional analyses identify pericyte-centered signaling programs altered by sex and brain region in Alzheimer’s Disease

Mon, 08 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 snRNA-seq and cell-cell communication modeling reveal sex and brain region specific pericyte signaling changes in Alzheimer’s Disease, implicating TGFβ activation, estrogen pathway loss, and inflammatory programs in neurovascular dysfunction.

Neurobehavioural genes exert indirect genetic effects on blood lipid profiles through behavioural traits

Mon, 08 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Family-based analyses reveal that indirect genetic effects on lipid profiles possess a genomic architecture distinct from direct genetic effects, mapping to neurobehavioral genes and acting through lifestyle mediators.

A multiparty homomorphic encryption approach to confidential federated Kaplan–Meier survival analysis

Mon, 08 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Highest h-index author on this paper: Jan F. Nygård (h-index 31) That author's affiliation: Norwegian Institute of Public Health Institution (first & last author): Norwegian Institute of Public Health A multiparty homomorphic encryption approach to confidential federated Kaplan–Meier survival analysis

Reconciling how clinical reasoning is learned in the age of artificial intelligence

Mon, 08 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Two recent studies examine the role of AI in supporting medical students’ learning – a longitudinal study of self-reported outcomes from supervised real-world AI use, and a simulated experiment comparing the benefits of AI explanations against the risks of plausible misinformation. Collectively, their findings demonstrate that the effects of AI may depend on the individual and educational environment, which has implications for how we design medical curricula and define clinical competence.

AS-IV attenuates nigral NLRP3 inflammasome in a Parkinson’s disease mouse model via gut microbiota

Sat, 06 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Astragaloside IV (AS-IV) exerts neuroprotective effects on ROT-induced Parkinson’s disease pathology through the microbiota-gut-brain axis mechanism.

Human-AI co-design for clinical prediction models

Sat, 06 Jun 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Highest h-index author on this paper: Chandan Singh (h-index 28) Institution (first & last author): Unknown Human-AI co-design for clinical prediction models

Developmental CA2 perineuronal net reduction restores social memory in Shank3 mutant mice

Fri, 05 Jun 2026 00:00:00 +0000

reply.relevance=9 reply.impact=9 Highest h-index author on this paper: Elizabeth Gould (h-index 87) That author's affiliation: Princeton University Institution (first & last author): Princeton University Correcting atypical development of perineuronal nets in hippocampal area CA2 prevents impaired circuit maturation and enables healthy social recognition in Shank3B knockout mice, a model relevant to ASD

Learning like a radiologist: a medical vision-language model for radiological image analysis via curriculum learning

Fri, 05 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 Highest h-index author on this paper: Xiaohuan Cao (h-index 23) Institution (first & last author): Unknown Learning like a radiologist: a medical vision-language model for radiological image analysis via curriculum learning

Agentic AI in global health equity for high altitude populations

Fri, 05 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Highest h-index author on this paper: Wu Yuan (h-index 44) That author's affiliation: Chinese University of Hong Kong Institution (first & last author): Chinese University of Hong Kong Agentic AI in global health equity for high altitude populations

BK channel overactivity in NAc core D1R-expressing neurons elevates anxiety with age in mice

Thu, 04 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=5 Highest h-index author on this paper: Qiang Shan (h-index 12) Institution (first & last author): Unknown Age-related enhancement of BK channel activity suppresses NAc core D1R-MSN activity, driving elevated basal anxiety-like behaviors in mice. Targeting this pathway offers a novel pharmacotherapeutic strategy for treating geriatric anxiety disorders.

Peptide occupancy governs HLA-E checkpoint interactions enabling VISTA recognition of destabilized HLA-E conformers

Thu, 04 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 VISTA recognizes peptide-deficient HLA-E, revealing peptide occupancy as a conformational switch for checkpoint receptor selectivity distinct from VL9 loaded HLA-E recognition by NKG2A and peptide independent binding by LILRB1/II.

Cardiac-derived extracellular vesicles carrying miR-4433b-3p accelerate cognitive decline and brain aging by suppressing TP53INP2-mediated neuronal autophagy in mice

Thu, 04 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=8 Cardiac aging signals propagate to the brain via miR-4433b-3p–enriched extracellular vesicles that disrupt neuronal autophagy and accelerate brain aging in mice.

Interpretable graph deep learning framework for drug synergy prediction by integrating functional and clinical similarities

Wed, 03 Jun 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Highest h-index author on this paper: Yongbao Zhang (h-index 11) That author's affiliation: Harbin Medical University Institution (first & last author): Harbin Medical University Interpretable graph deep learning framework for drug synergy prediction by integrating functional and clinical similarities

Clinical outcomes and reporting quality of large language model interventions in practice: a systematic evidence map

Tue, 02 Jun 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Clinical outcomes and reporting quality of large language model interventions in practice: a systematic evidence map

AI home monitoring for behavioral markers of cerebrovascular disease

Tue, 02 Jun 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 AI home monitoring for behavioral markers of cerebrovascular disease

Reclaiming informed consent to train mental health AI with patient data

Tue, 02 Jun 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Companies increasingly train AI models on therapy transcripts, often relying on terms of service that obscure data use to obtain assent. Because AI systems generate inferences from data and enable unforeseen secondary uses, existing consent models do not adequately protect autonomy and confidentiality. We argue for (1) separate and explicit opt-in consent to train on patient data and (2) patient-led governance to prevent the recurrence of exploitation in medical innovation.

Emerging roles of ferroptosis in modulating the immune landscape of glial tumours

Mon, 01 Jun 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: Betty Y.S. Kim (h-index 49) That author's affiliation: The University of Texas MD Anderson Cancer Center Institution (first & last author): Columbia University Irving Medical Center This Review discusses the roles of ferroptosis in shaping the immune landscape in glial tumours and highlights potential strategies that combine ferroptosis induction with immunotherapy for a durable control of gliomas.

Identification of moderate effect size genes in autism spectrum disorder through a novel gene pairing approach

Sat, 30 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: Joseph D. Buxbaum (h-index 141) That author's affiliation: Allen Institute for Brain Science First author institution: Icahn School of Medicine at Mount Sinai Last author institution: Karolinska Institutet Pairwise inheritance modelling uncovers moderate-effect autism spectrum disorder genes lacking single-gene association but jointly conferring risk, identifying 97 genes in 50 pairs and highlighting subthreshold genetic effects.

Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Sat, 30 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=5 Droplet microfluidics with image texture quantification for detection of rare antibiotic-resistant subpopulations from bloodstream infections

Sensor wide association studies in digital medicine

Sat, 30 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Nico Steckhan (h-index 23) That author's affiliation: Hasso Plattner Institute First author institution: Hasso Plattner Institute Last author institution: University of Stirling Sensor wide association studies in digital medicine

Brain regions with gestational age differences mediate cognition in adolescents born very premature

Fri, 29 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Highest h-index author on this paper: Teddy Jakim (h-index 1) Institution (first & last author): Unknown Analysis of adolescent grey and white matter measures highlights persistent neuronal developmental differences associated with very premature birth. These neuronal differences mediated the very premature adolescents’ lower cognitive performance.

Cognitive load weakens neural speech tracking without altering response timing

Fri, 29 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Highest h-index author on this paper: Ruixiang Liu (h-index 0) That author's affiliation: China Medical University Institution (first & last author): China Medical University Cognitive load weakens neural tracking of continuous speech and alters frontotemporal coupling without shifting the timing of speechrelated brain responses.

Efficacy of AI-delivered cognitive behavioral therapy interventions for anxiety and depressive symptoms: a systematic review

Fri, 29 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 Highest h-index author on this paper: David Stückler (h-index 97) That author's affiliation: Bocconi University First author institution: University of Oxford Last author institution: Bocconi University Efficacy of AI-delivered cognitive behavioral therapy interventions for anxiety and depressive symptoms: a systematic review

Effectiveness of AI and rule-based conversational agents for depression, anxiety and stress: A meta-analysis

Fri, 29 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Abouzar Nazari (h-index 6) That author's affiliation: Shahrekord University of Medical Sciences First author institution: Shiraz University Last author institution: Shahrekord University of Medical Sciences Effectiveness of AI and rule-based conversational agents for depression, anxiety and stress: A meta-analysis

Structural basis of Fumosorinone-mediated allosteric inhibition of PTP1B for cancer immunotherapy

Thu, 28 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 This study defines a previously uncharacterized allosteric pocket in Protein Tyrosine Phosphatase 1B that locks the enzyme in an inactive state, enabling selective inhibition and structure-guided immunotherapy design.

A clinical neuroimaging platform for rapid, automated lesion detection and personalized post-stroke outcome prediction

Wed, 27 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: Hans J. Johnson (h-index 50) That author's affiliation: University of Iowa Institution (first & last author): University of Iowa A clinical neuroimaging platform for rapid, automated lesion detection and personalized post-stroke outcome prediction

Personalised thrombo-embolic risk prediction after endometrial cancer surgery: an explainable AI approach using SHAP

Wed, 27 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=5 Highest h-index author on this paper: Lin Xu (h-index 46) That author's affiliation: Guizhou Cancer Hospital Institution (first & last author): Zunyi Medical University Personalised thrombo-embolic risk prediction after endometrial cancer surgery: an explainable AI approach using SHAP

Multicenter randomized trial of a digital therapeutic game for executive function in children with ADHD

Wed, 27 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Highest h-index author on this paper: Johanna Inhyang Kim (h-index 26) That author's affiliation: Hanyang University Institution (first & last author): Seoul National University Multicenter randomized trial of a digital therapeutic game for executive function in children with ADHD

ICIsAtlas reveals a suppressive NK cell niche in pan-cancer immunotherapy profiles

Tue, 26 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 Highest h-index author on this paper: Yanxin Luo (h-index 32) Institution (first & last author): Unknown ICIsAtlas integrates pan-cancer transcriptomic profiles of patients receiving checkpoint blockade to reveal response-associated tumour cell states and a suppressive niche mediated by an NK cell state linked to resistance.

Dual targeting of glutamine metabolism and lysosomal function in eliminating drug-tolerant KRAS-mutant cancer cells

Tue, 26 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Drug-tolerant persister cells limit the durability of KRAS inhibitor therapy. Dual targeting of glutamine metabolism and lysosome-associated processes exposes a redox-linked vulnerability in drug-tolerant KRAS-mutant cancer cells.

The shape of attention reflects flexible filtering of natural speech modulations

Sun, 24 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=6 Highest h-index author on this paper: Mounya Elhilali (h-index 33) That author's affiliation: Johns Hopkins University Institution (first & last author): Johns Hopkins University This study tests how attention shapes neural speech representations. Using EEG, speech-in-noise was heard during comprehension or identification tasks. A novel Modulation Response Function shows goal-dependent feature emphasis over uniform attention.

Divalent aptamer-mediated clustering for extracellular vesicle separation

Sat, 23 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Highest h-index author on this paper: Taiyi Zhang (h-index 10) That author's affiliation: Beijing Normal-Hong Kong Baptist University Institution (first & last author): Beijing Normal-Hong Kong Baptist University Divalent aptamers drive extracellular vesicle clustering to enable streamlined isolation of intact and functional EVs, offering a versatile platform for probing EV heterogeneity and biomolecular cargo.

FGFR3 oncogenic activation drives oxidative metabolic reprogramming in bladder cancer: a systems metabolomics approach

Sat, 23 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=7 A multi-omics study demonstrates that FGFR3 oncogenic activation drives oxidative metabolic reprogramming in bladder cancer. These findings highlight a vulnerability to mitochondrial inhibitors as a precision therapy for FGFR3-altered tumours.

Direct electrical stimulation of the human amygdala enhances recognition memory for objects but not scenes

Fri, 22 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Stephan Hamann (h-index 48) That author's affiliation: Emory University Institution (first & last author): University of Utah Direct electrical stimulation of the human amygdala influences the specificity of what information is prioritized in memory and provides insight into how amygdala-MTL projections contribute to the dynamics of memory enhancement.

A multilevel meta-analysis of passive smartphone sensing of adolescent mental health

Fri, 22 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 A multilevel meta-analysis of passive smartphone sensing of adolescent mental health

Expert perspectives on the ecosystem of medical AI oversight in the GenAI era

Fri, 22 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 In this third article of a three-article series on interviews with Dr Shantanu Nundy, an advisor in the office of the Commissioner of the US FDA on AI governance and digital health policy, we explore how the oversight of generative AI (GenAI) and large language model (LLM)-enabled medical devices extends beyond the remit of any single regulator, requiring coordination among government agencies, health systems, and practicing clinicians. We also discuss practical advice for innovators seeking to engage productively with the FDA.

Stress granules shape ferroptosis in cancer

Fri, 22 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 A major obstacle in treating glioblastoma is the remarkable resistance of glioblastoma stem cells to standard-of-care therapies such as temozolomide and irradiation. A new study now reveals that dismantling protective structures called stress granules can make these cells more susceptible to these treatment regimens by unleashing ferroptosis.

Stress granules restrain ferroptosis by sequestering ferritin

Fri, 22 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Ge, Wang, Zhao, Guo et al. report a role for stress granules in suppressing ferroptosis by sequestering ferritin upon irradiation and temozolomide treatment in glioblastoma stem cells, which may potentially be targeted for improved efficacy.

Lysophosphatidic acid drives to mirror-image pain via corpus callosum-mediated propagation of inflammatory responses

Wed, 20 May 2026 00:00:00 +0000

reply.relevance=9 reply.impact=8 Lysophosphatidic acid (LPA) drives stroke-induced mirror-image pain by propagating inflammatory signals through the corpus callosum, involving LPA amplification, microglial activation, and increased PGE2 production in the contralateral cortex.

Enhanced expression of spinal PTP1B contributes to peripheral inflammation- induced glycinergic disinhibition and mechanical pain

Wed, 20 May 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Alternative interactions of GlyR α1 with PTP1B and GPR39 in somatostatin-positive interneurons of spinal dorsal horn reveal how peripheral inflammation leads to glycinergic disinhibition and mechanical pain hypersensitivity

Optimizing AI implementation for surgery: recommendations for infrastructure and deployment in the operating room

Wed, 20 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 Optimizing AI implementation for surgery: recommendations for infrastructure and deployment in the operating room

Brain-wide information flow dynamics during novel visual processing in humans

Mon, 18 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Shanshan Liang (h-index 23) Institution (first & last author): Unknown Human intracranial recordings reveal millisecond-scale visual flow from occipital cortex along parallel dorsal and ventral pathways to frontal and limbic regions, with category-specific dynamics for faces and places during novel visual processing.

A deep learning model to dynamically predict cancer-associated thromboembolism in large-scale healthcare systems

Mon, 18 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 A deep learning model to dynamically predict cancer-associated thromboembolism in large-scale healthcare systems

Expert perspectives on recent US digital medicine regulation policy changes and the TEMPO pilot

Mon, 18 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 To enable progress in digital medicine and medical AI, particularly where these technologies extend beyond the usual boundaries of medical devices, new regulatory approaches are needed. In this first article of a three-part interview series with Dr Shantanu Nundy, an advisor on AI in the FDA Commissioner’s Office, we examine the agency’s newly announced TEMPO pilot. The pilot aims to create new pathways for digital health in chronic disease by linking oversight, evidence generation, and reimbursement.

Oscillatory network efficiency predicts mood and fatigue during sleep deprivation

Sat, 16 May 2026 00:00:00 +0000

reply.relevance=7 reply.impact=6 Highest h-index author on this paper: Daniel B. Forger (h-index 39) First author institution: University of Arizona Last author institution: Unknown Efficiency of regional networks in frontal, limbic, and sensorimotor regions show unique oscillatory patterns of reorganization. Variation in psychomotor vigilance, fatigue, and negative affect reflect dynamic changes in functional network topology.

Multi-task deep learning assists detection and diagnosis of gliomas and brain metastases

Sat, 16 May 2026 00:00:00 +0000

reply.relevance=8 reply.impact=7 Multi-task deep learning assists detection and diagnosis of gliomas and brain metastases

A dynamic risk prediction framework for Alzheimer's disease and related dementias with interpretability

Fri, 15 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=7 Highest h-index author on this paper: Sunyang Fu (h-index 23) Institution (first & last author): Unknown A dynamic risk prediction framework for Alzheimer's disease and related dementias with interpretability

Mechanisms and functions of large extracellular vesicle biogenesis

Fri, 15 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=6 This Review presents the formation of large extracellular vesicle (L-EV) subsets, highlighting that their contents and physiological relevance, for example, in intercellular communication, are driven by the different mechanisms underlying their biogenesis.

A human-in-the-loop explanation framework for morphologically transparent AI predictions from whole-slide images

Thu, 14 May 2026 00:00:00 +0000

reply.relevance=6 reply.impact=6 Highest h-index author on this paper: Nicholas Chia (h-index 52) That author's affiliation: Argonne National Laboratory Institution (first & last author): Mayo Clinic A human-in-the-loop explanation framework for morphologically transparent AI predictions from whole-slide images

A foundational model encodes deep phenotyping data and enables diverse downstream applications

Thu, 14 May 2026 00:00:00 +0000

reply.relevance=5 reply.impact=7 A foundational model encodes deep phenotyping data and enables diverse downstream applications

Shared subcortical–default mode morphological dysconnectivity in adolescent bipolar disorder, major depressive disorder and schizophrenia